Interleukin-12 gene polymorphism in children with BCG-osis from Iran
نویسندگان
چکیده
منابع مشابه
Cytokine Gene Polymorphism in BCG Lymphadenopathy
Background: Tumor necrosis factor-beta or lymphotoxin-alpha (LT-α), IL-4 and IL-10 are determining factors in immunity against BCG. Allelic polymorphisms in the regulatory regions of their genes affect the rate of cytokine production and therefore, the host’s ability in BCG containment. Objective: To study the prevalence of –590 (C/T) and –592 (C/A) allelic distribution of IL-4 and IL-10 promo...
متن کاملBCG-osis after BCG vaccination in immunocompromised children: Case series and review
*Corresponding Author: Mohammad Sadegh Rezai MD, Associate professor of pediatric infectious diseases Mailing Address: Department of Pediatric Infectious Disease, Antimicrobial Resistant Nosocomial Infection Research Centre, Bou Ali Sina Hospital, Pasdaran Boulevard, Sari, Iran. Tel: +98 151 2233011-15 Fax: +98 151 2234506 Email: [email protected] BCG-osis after BCG vaccination in immunocom...
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Intravesical instillation of Bacillus Calmette-Guérin (BCG) has been shown to be an effective form of immunotherapy for bladder cancer. This case report describes a patient who develops systemic BCG-osis following intravesical BCG instillation and demonstrates the importance of being aware of more severe complications associated with BCG immunotherapy.
متن کاملThe Role of Interleukin 1β Gene Polymorphism in Gastric Cancer in North-eastern Iran
Background and Objective: Host genetic factors such as cytokine gene polymorphisms as well as Helicobacter pylori (H. pylori) infection have been found to be associated with gastric cancer risk . Interleukin 1 is a pro-inflammatory cytokine involved in H. pylori-induced gastric inflammation. Therefore, w...
متن کاملcytokine gene polymorphism in bcg lymphadenopathy
background: tumor necrosis factor-beta or lymphotoxin-alpha (lt- α ), il-4 and il-10 are determining factors in immunity against bcg. allelic polymorphisms in the regulatory regions of their genes affect the rate of cytokine production and therefore, the host’s ability in bcg containment. objective : to study the prevalence of –590 (c/t) and –592 (c/a) allelic distribution of il-4 and il-10 ...
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ژورنال
عنوان ژورنال: International Journal of Mycobacteriology
سال: 2015
ISSN: 2212-5531
DOI: 10.1016/j.ijmyco.2014.11.008